Genetics of Development and Regeneration
Florenci Serras
Mora I, Puiggròs F, Serras F, Gil-Cardoso K, Escoté X. Emerging models for studying adipose tissue metabolism. Biochem Pharmacol. 2024 May;223:116123. doi: 10.1016/j.bcp.2024.116123.
Serras F. The sooner, the better: ROS, kinases and nutrients at the onset of the damage response in Drosophila. Front Cell Dev Biol. 2022 Oct 24;10:1047823. doi: 10.3389/fcell.2022.1047823.
Climent-Cantó P, Molnar C, Santabárbara-Ruiz P, Prieto C, Abril JF, Serras F, Gonzalez C. Oxidative Stress Is Associated with Overgrowth in Drosophila l(3)mbt Mutant Imaginal Discs. Cells. 2022; 11(16):2542.
Esteban-Collado J, Corominas M, Serras F. Nutrition and PI3K/Akt signaling are required for p38-dependent regeneration. Development. 2021 Apr 15;148(8):dev197087. doi: 10.1242/dev.197087. Epub 2021 Apr 23. PMID: 33913483.
Camilleri-Robles C, Serras F, Corominas M. Role of D-GADD45 in JNK-Dependent Apoptosis and Regeneration in Drosophila. Genes (Basel). 2019 May 18;10(5). pii: E378. doi: 10.3390/genes10050378.
Vizcaya-Molina E, Klein CC, Serras F, Corominas M. Chromatin dynamics in regeneration epithelia: Lessons from Drosophila imaginal discs. Semin Cell Dev Biol. 2019 May 16. pii: S1084-9521(18)30195-2. doi: 10.1016/j.semcdb.2019.04.017.
Reuter H, Vogg MC, Serras F. Repair, regenerate and reconstruct: meeting the state-of-the-art. Development. 2019 May 8;146(9):dev176974. doi: 10.1242/dev.176974. PMID: 31068375.
Santabárbara-Ruiz P, Esteban-Collado J, Pérez L, Viola G, Abril JF, Milán M, Corominas M, Serras F. Ask1 and Akt act synergistically to promote ROS-dependent regeneration in Drosophila. PLoS Genet. 2019 Jan 24;15(1):e1007926
Vizcaya-Molina E, Klein CC, Serras F, Mishra RK, Guigó R, Corominas M. Damage-responsive elements in Drosophila regeneration. Genome Res. 2018 Dec;28(12):1852-1866.
Mercader N, Serras F. Elly Tanaka's passion for exploring animal regeneration. Int J Dev Biol. 2018;62(6-7-8):387-391. doi: 10.1387/ijdb.180049fs.
Mercader N, Serras F. Can broken hearts be mended? Ken Poss, a pioneer on heart regeneration research. Int J Dev Biol. 2018;62(6-7-8):383-386. doi: 10.1387/ijdb.180088fs.
Mercader N, Serras F. Models to crack the code of organ regeneration. Int J Dev Biol. 2018;62(6-7-8):347-350. doi: 10.1387/ijdb.180105fs.
Hariharan, IK and Serras, F. Imaginal disc regeneration takes flight. Curr Opin Cell Biol. 2017 48:10-16.
Serras F. The benefits of oxidative stress for tissue repair and regeneration. Fly (Austin). 2016 Jul 2;10(3):128-33. doi: 10.1080/19336934.2016.1188232.
Santabárbara-Ruiz P, López-Santillán M, Martínez-Rodríguez I, Binagui-Casas A, Pérez L, Milán M, Corominas M, Serras F. ROS-Induced JNK and p38 Signaling Is Required for Unpaired Cytokine Activation during Drosophila Regeneration. PLoS Genet. 2015 Oct 23;11(10):e1005595. doi: 10.1371/journal.pgen.1005595.
Mariotti M, Santesmasses D, Capella-Gutierrez S, Mateo A, Arnan C, Johnson R, D'Aniello S, Yim SH, Gladyshev VN, Serras F, Corominas M, Gabaldón T, Guigó R. Evolution of selenophosphate synthetases: emergence and relocation of function through independent duplications and recurrent subfunctionalization. Genome Res. 2015 Sep;25(9):1256-67. doi: 10.1101/gr.190538.115.
Ruiz-Romero M, Blanco E, Paricio N, Serras F, Corominas M. Cabut/dTIEG associates with the transcription factor Yorkie for growth control. EMBO Rep.2015 Mar;16(3):362-9. doi: 10.15252/embr.201439193.
Alaña L, Sesé M, Cánovas V, Punyal Y, Fernández Y, Abasolo I, de Torres I, Ruiz C, Espinosa L, Bigas A, Y Cajal SR, Fernández PL, Serras F, Corominas M, Thomson TM, Paciucci R. Prostate tumor OVerexpressed-1 (PTOV1) down-regulates HES1 and HEY1 notch targets genes and promotes prostate cancer progression. Mol Cancer. 2014 Mar 31;13:74. doi: 10.1186/1476-4598-13-74.
Repiso A, Bergantiños C, Serras F. Cell fate respecification and cell division orientation drive intercalary regeneration in Drosophila wing discs. Development. 2013 Sep;140(17):3541-51. doi: 10.1242/dev.095760.
Carbonell A, Mazo A, Serras F, Corominas M. Ash2 acts as an ecdysone receptor coactivator by stabilizing the histone methyltransferase Trr. Mol Biol Cell. 2013 Feb;24(3):361-72. doi: 10.1091/mbc.E12-04-0267.
Mora N, Almudi I, Alsina B, Corominas M, Serras F. β amyloid protein precursor-like (Appl) is a Ras1/MAPK-regulated gene required for axonal targeting in Drosophila photoreceptor neurons. J Cell Sci. 2013 Jan 1;126(Pt 1):53-9. doi: 10.1242/jcs.114785.
Mora N, Santa Bárbara Ruiz P, Ferreira N, Serras F. Ras signal triggers β-amyloid precursor protein (APP) expression. Small GTPases. 2013 Jul-Sep;4(3):171-3. doi: 10.4161/sgtp.24768.
Pérez-Lluch S, Blanco E, Carbonell A, Raha D, Snyder M, Serras F, Corominas M. Genome-wide chromatin occupancy analysis reveals a role for ASH2 in transcriptional pausing. Nucleic Acids Res. 2011 Jun;39(11):4628-39. doi: 10.1093/nar/gkq1322.
Repiso A, Bergantiños C, Corominas M, Serras F. Tissue repair and regeneration in Drosophila imaginal discs. Dev Growth Differ. 2011 Feb;53(2):177-85. doi: 10.1111/j.1440-169X.2010.01247.x.
Almudi I, Corominas M, Serras F. Competition between SOCS36E and Drk modulates Sevenless receptor tyrosine kinase activity. J Cell Sci. 2010 Nov 15;123(Pt 22):3857-62. doi: 10.1242/jcs.071134.
Blanco E, Ruiz-Romero M, Beltran S, Bosch M, Punset A, Serras F, Corominas M. Gene expression following induction of regeneration in Drosophila wing imaginal discs. Expression profile of regenerating wing discs. BMC Dev Biol. 2010 Sep 2;10:94. doi: 10.118
Bergantiños C, Corominas M, Serras F. Cell death-induced regeneration in wing imaginal discs requires JNK signalling. Development. 2010 Apr;137(7):1169-79. doi: 10.1242/dev.045559.
Bergantiños C, Vilana X, Corominas M, Serras F. Imaginal discs: Renaissance of a model for regenerative biology. Bioessays. 2010 Mar;32(3):207-17. doi: 10.1002/bies.200900105.
Galletti M, Riccardo S, Parisi F, Lora C, Saqcena MK, Rivas L, Wong B, Serra A, Serras F, Grifoni D, Pelicci P, Jiang J, Bellosta P. Identification of domains responsible for ubiquitin-dependent degradation of dMyc by glycogen synthase kinase 3beta and casein kinase 1 kinases. Mol Cell Biol 29(12): 3424–3434.
Almudi I, Stocker H, Hafen E, Corominas M, Serras F. SOCS36E specifically interferes with Sevenless signaling during Drosophila eye development. Dev Biol. 2009 Feb 1;326(1):212-23. doi: 10.1016/j.ydbio.2008.11.014.
Bosch M, Baguñà J, Serras F. Origin and proliferation of blastema cells during regeneration of Drosophila wing imaginal discs. Int J Dev Biol. 2008;52(8):1043-50. doi: 10.1387/ijdb.082608mb.
Ryder E, Ashburner M, Bautista-Llacer R, Drummond J, Webster J, Johnson G, Morley T, Chan YS, Blows F, Coulson D, Reuter G, Baisch H, Apelt C, Kauk A, Rudolph T, Kube M, Klimm M, Nickel C, Szidonya J, Maróy P, Pal M, Rasmuson-Lestander A, Ekström K, Stocker H, Hugentobler C, Hafen E, Gubb D, Pflugfelder G, Dorner C, Mechler B, Schenkel H, Marhold J, Serras F, Corominas M, Punset A, Roote J, Russell S. The DrosDel deletion collection: a Drosophila genomewide chromosomal deficiency resource. Genetics. 2007 Sep;177(1):615-29.
Bosch M, Serras F, Martín-Blanco E, Baguñà J. JNK signaling pathway required for wound healing in regenerating Drosophila wing imaginal discs. Dev Biol. 2005 Apr 1;280(1):73-86.
Dunlop J, Morin X, Corominas M, Serras F, Tear G. glaikit is essential for the formation of epithelial polarity and neuronal development. Curr Biol. 2004 Nov 23;14(22):2039-45.
Angulo M, Corominas M, Serras F. Activation and repression activities of ash2 in Drosophila wing imaginal discs. Development. 2004 Oct;131(20):4943-53.
Morey M, Corominas M, Serras F. DIAP1 suppresses ROS-induced apoptosis caused by impairment of the selD/sps1 homolog in Drosophila. J Cell Sci. 2003 Nov 15;116(Pt 22):4597-604.
Alsina B, Corominas M, Berry MJ, Baguñà J, Serras F. Disruption of selenoprotein biosynthesis affects cell proliferation in the imaginal discs and brain of Drosophila melanogaster. J Cell Sci. 1999 Sep;112 ( Pt 17):2875-84.
