PUBLICACIONES
Exploration of moisture activated dry granulation for the development of gastroretentive tablets aided by SeDeM diagram
MX Origoni et al. European Journal of Pharmaceutics and Biopharmaceutics. 2024, 203, 114456
https://doi.org/10.1016/j.ejpb.2024.114456
Application of Galenic Strategies for Developing Gastro-Resistant Omeprazole Formulation for Pediatrics
K. Rouaz-El-Hajoui et al. Children. 2024, 11, 945
https://doi.org/10.3390/children11080945
Development of cationic solid lipid nanoparticles incorporating cholesteryl-9-carboxynonanoate (9CCN) for delivery of antagomiRs to macrophages
A. Mallén et al. European Journal of Pharmaceutics and Biopharmaceutics. 2024, 197, 114238.
https://doi.org/10.1016/j.ejpb.2024.114238
Development of a Carvedilol Oral Liquid Formulation for Paediatric Use
B. Chiclana-Rodriguez et al. Pharmaceutics. 2023, 15, 2283.
https://doi.org/10.3390/pharmaceutics15092283
Pellets and gummies: Seeking a 3D printed gastro-resistant omeprazole dosage for paediatric administration
K. Rouaz-El Hajoui et al. International Journal of Pharmaceutics. 2023, 643, 123289.
https://doi.org/10.1016/j.ijpharm.2023.123289
Optimisation of the Manufacturing Process of Organic-Solvent-Free Omeprazole Enteric Pellets for the Paediatric Population: Full Factorial Design
K. Rouaz-El Hajoui et al. Pharmaceutics. 2023, 15, 2587.
https://doi.org/10.3390/pharmaceutics15112587
Methods for Developing a Process Design Space Using Retrospective Data
M. Romero-Ubon et al. Pharmaceutics. 2023, 15, 2629.
https://doi.org/10.3390/pharmaceutics15112629
Improvement of the Pour Plate Method by Separate Sterilization of Agar and Other Medium Components and Reduction of the Agar Concentration
I. Terrones-Fernandez et al. Microbiology Spectrum. 2023, 11(1).
https://doi.org/10.1128/spectrum.03161-22
Dialysis is a key factor modulating interactions between critical process parameters during the microfluidic preparation of lipid nanoparticles
R. Vargas et al. Colloid And Interface Science Communications. 2023, 100709.
https://doi.org/10.1016/j.colcom.2023.100709
SeDeM as a Tool to Validate Drug Substance Manufacturing Processes and Assess Scalability and Suitability for Direct Compression: Supplier Screening
A. Figuera-Figuera et al. Pharmaceutics. 2023, 15(8), 2034.
https://doi.org/10.3390/pharmaceutics15082034
Comparative Analysis of the Physicochemical and Biological Characteristics of Freeze-Dried PEGylated Cationic Solid Lipid Nanoparticles
D. A Narváez et al. Pharmaceutics. 2023, 16(11), 1583.
https://doi.org/10.3390/ph16111583
Formulation and development of paediatric orally disintegrating carbamazepine tablets
R. Canadell-Heredia et al. Saudi Pharm J. 2022, 30(11), 1612-1622.
https://doi.org/10.1016/j.jsps.2022.09.004
Improvement of Mueller-Kauffman Tetrathionate-Novobiocin (MKTTn) enrichment medium for the detection of Salmonella enterica by the addition of ex situ-generated tetrathionate
M. Torrico et al. J Microbiol Methods. 2022, 199, 106524.
https://doi.org/10.1016/j.mimet.2022.106524
Development of a Standardized Method for Measuring Bioadhesion and Mucoadhesion That Is Applicable to Various Pharmaceutical Dosage Forms
L. Amorós-Galicia et al. Pharmaceutics. 2022, 14(10), 1995.
https://doi.org/10.3390/pharmaceutics14101995
Buenas prácticas para un programa de limpieza efectivo
E. García Montoya. PHARMATECH. 2021, 61.
https://diposit.ub.edu/dspace/bitstream/2445/183485/1/717781.pdf
ICH Q12: innovadora y controvertida (parte 1)
L. Monsonís Centelles et al. PHARMATECH. 2021, 58.
https://diposit.ub.edu/dspace/bitstream/2445/181479/1/715533.pdf
ICH Q12: innovadora y controvertida (parte 2)
L. Monsonís Centelles et al. PHARMATECH. 2021, 60.
https://diposit.ub.edu/dspace/bitstream/2445/183451/1/717780.pdf
Spatiotemporal Analysis of Hydration Mechanism in Sodium Alginate Matrix Tablets
E. Juszczyk et al. Materials. 2021, 14, 646.
https://doi.org/10.3390/ma14030646
Hydration Patterns in Sodium Alginate Polymeric Matrix Tablets—The Result of Drug Substance Incorporation
E. Juszczyk et al. Materials. 2021, 14(21), 6531.
https://doi.org/10.3390/ma14216531
A new SeDeM-SLA expert system for screening of solid carriers for the preparation of solidified liquids: A case of citronella oil
Devanishi. S. Shah et al. Powder Technology. 2021, 382, 605-618.
https://doi.org/10.1016/j.powtec.2021.01.019
Excipients in the Paediatric Population: A Review
Khadija Rouaz et al. Pharmaceutics. 2021, 13, 387.
https://doi.org/10.3390/pharmaceutics13030387
Therapeutic potential of nicotinamide adenine dinucleotide (NAD)
M. Arenas-Jal et al. European Journal of Pharmacology. 2020, 879, 173158.
https://doi.org/10.1016/j.ejphar.2020.173158
3D printed gummies: Personalized drug dosage in a safe and appealing way
H. Herrada-Manchón et al. European Journal of Pharmacology. 2020, 587, 119687.
https://doi.org/10.1016/j.ijpharm.2020.119687
Robustness Optimization of an Existing Tablet Coating Process Applying Retrospective Knowledge (rQbD) and Validation
A. Galí et al. Pharmaceutics. 2020, 12(8), 743.
https://doi.org/10.3390/pharmaceutics12080743
Formulation of Sustained Release Hydrophilic Matrix Tablets of Tolcapone with the Application of Sedem Diagram: Influence of Tolcapone’s Particle Size on Sustained Release
A. Nardi-Ricart et al. Pharmaceutics. 2020, 12(7), 674.
https://doi.org/10.3390/pharmaceutics12070674
Coenzyme Q10 supplementation: Efficacy, safety, and formulation challenges
M. Arenas-Jal et al. Comprehensive Reviews in Food Science and Food Safety. 2020, 19(2), 574.
https://doi.org/10.1111/1541-4337.12539
An overview of microencapsulation in the food industry: opportunities, challenges, and innovations
M. Arenas-Jal et al. European Food Research and Technology. 2020, 246, 1371.
https://doi.org/10.1007/s00217-020-03496-x
Study of tocopherol content and its potential antioxidant activity in commercial lipid emulsions for parenteral nutrition
A. Novak et al. Pharmazie. 2020, 75, 240.
https://pubmed.ncbi.nlm.nih.gov/32539917/
Formulation of Direct Compression Zidovudine Tablets to Correlate the SeDeM Diagram Expert System and the Rotary Press Simulator Styl’ONE Results
I. Nofrerias et al. AAPS PharmSciTech. 2020, 21, 1.
https://doi.org/10.1208/s12249-019-1542-5
Trends in the food and sports nutrition industry: A review
M. Arenas et al. Critical Reviews in Food Science and Nutrition. 2020, 60 (15), 2405.
https://doi.org/10.1080/10408398.2019.1643287
Comparison between Microcrystalline Celluloses of different grades made by four manufacturers using the SeDeM diagram expert system as a pharmaceutical characterization tool
I. Nofrerias et al. Powder Technology. 2019, 342, 780.
https://doi.org/10.1016/j.powtec.2018.10.048
Development and Validation of a New High-Performance Liquid Chromatography Method for the Simultaneous Quantification of Coenzyme Q10, Phosphatidylserine, and Vitamin C from a Cutting-Edge Liposomal Vehiculization
M. Ruiz-García et al. ACS Omega 2019, 4, 22, 19710–19715.
https://doi.org/10.1021/acsomega.9b02456
Improved synthesis and characterization of cholesteryl oleate-loaded cationic solid lipid nanoparticles with high transfection efficiency for gene therapy applicationsiposomal Vehiculization
M. Suñé-Pou et al. Colloids and Surfaces B: Biointerfaces. 2019, 180, 159-167.
https://doi.org/10.1016/j.colsurfb.2019.04.037
Optimization of the Cohesion Index in the SeDeM Diagram Expert System and application of SeDeM Diagram: An improved methodology to determine the Cohesion Index
I. Nofrerias et al. PLOS ONE. 2018.
https://doi.org/10.1371/journal.pone.0203846
A new design for the review and appraisal of semi-solid dosage forms: Semi-solid Control Diagram (SSCD)
A. Nardi-Ricart et al. PLOS ONE. 2018.
https://doi.org/10.1371/journal.pone.0201643
Osmolality predictive models of different polymers as tools in parenteral and ophthalmic formulation development
D. Arbelaez-Camargo et al. International Journal of Pharmaceutics. 2018, 543 (1-2), 190-200.
https://doi.org/10.1016/j.ijpharm.2018.03.052
Topical Analgesia with Lidocaine Plus Diclofenac Decreases Pain in Benign Anorectal Surgery: Randomized, Doubleblind, and Controlled Clinical Trial
M.J. Linares-Gil et al. Clinical and Translational Gastroenterology. 2018, 9(11).
10.1038/s41424-018-0075-7
The role of SeDeM for characterizing the active substance and polyvinyilpyrrolidone eliminating metastable forms in an oral lyophilizate—A preformulation study
P. Flórez et al. PLOS ONE. 2018.
https://doi.org/10.1371/journal.pone.0196049
Development and validation of a simple high-performance liquid chromatography analytical method for simultaneous determination of phytosterols, cholesterol and squalene in parenteral lipid emulsions
A. Novak et al. Biomedical Chromatography. 2018, 32(2).
https://doi.org/10.1002/bmc.4084
Cholesteryl oleate-loaded cationic solid lipid nanoparticles as carriers for efficient gene-silencing therapy
M. Suñé-Pou et al. Int J Nanomedicine. 2018, 13, 3223-3233.
https://doi.org/10.2147/IJN.S158884
Optimization and Validation of a Fast UPLC Method for Simultaneous Determination of Hydroquinone, Kojic Acid, Octinoxate, Avobenzone, BHA, and BHT
F. Galimany-Rovira et al. Journal of AOAC International. 2017, 100(1), 1-7.
https://doi.org/10.5740/jaoacint.16-0104
Formulation and characterization of mucoadhesive controlled release matrix tablets of captopril
J. Saurí et al. Journal of Drug Delivery Science and Technology. 2017, 42, 215-226.
https://doi.org/10.1016/j.jddst.2017.03.009
Improved formulation of cationic solid lipid nanoparticles displays cellular uptake and biological activity of nucleic acids
A. Fàbregas et al. International Journal of Pharmaceutics. 2017, 516(1-2), 39-44.
https://doi.org/10.1016/j.ijpharm.2016.11.026
Gestión y optimización de los controles del proceso de envasado
J. Cobo Serrano et al. Pharmatech. 2016.
https://diposit.ub.edu/dspace/handle/2445/100504
Preformulation and characterization of a lidocaine hydrochloride and dexamethasone sodium phosphate thermo-reversible and bioadhesive long-acting gel for intraperitoneal administration
D. Arbelaez-Camargo et al. Pharmatech. 2016, 498(1-2), 142-152.
https://doi.org/10.1016/j.ijpharm.2015.12.012
Approach to design space from retrospective quality data
D. Puñal et al. Pharmaceutical Development and Technology. 2016, 21(1), 26-38.
https://doi.org/10.3109/10837450.2014.965321
Mejorar la solidez del recubrimiento de tabletas mediante la selección de parámetros críticos del proceso a partir de datos retrospectivos
A. Gali et al. Pharmaceutical Development and Technology. 2016, 21(6), 688-697.
https://doi.org/10.3109/10837450.2015.1045619
Development and validation of a new RP-HPLC method for simultaneous determination of hydroquinone, kojic acid, octinoxate, avobenzone, BHA and BHT in skin-whitening cream
F. Galimnay et al. Analytical Methods. 2016, 8(5), 1170-1180.
10.1039/C5AY02207J
Relationships between surface free energy, surface texture parameters and controlled drug release in hydrophilic matrices
J. Saurí et al. International Journal of Pharmaceutics. 2015, 478(1), 328-340.
https://doi.org/10.1016/j.ijpharm.2014.11.054
Modification of the morphology and particle size of pharmaceutical excipients by spray drying technique
R. Sarrate et al. Powder Technology. 2015, 270(part A), 244-255.
https://doi.org/10.1016/j.powtec.2014.08.021
Establecimiento del espacio de diseño a partir de datos industriales retrospectivos
D. Puñal et al. Pharmatech. 2015.
https://www.pharmatech.es/articulos/20150710/establecimiento-espacio-diseno-a-partir-datos-industriales-retrospectivos
Establishment of criteria for the selection and adaptation of objectives and indicators in ISO9001:2008 quality system in a university pharmaceutical pilot plant
A. Fàbregas et al. Ars Pharmaceutica. 2015.
https://dx.doi.org/10.4321/S2340-98942015000100003
Development and Validation of a Stability Indicating RP-HPLC Method for Hydrocortisone Acetate Active Ingredient, Propyl Parahydroxybenzoate and Methyl Parahydroxybenzoate Preservatives, Butylhydroxyanisole Antioxidant, and Their Degradation Products in a Rectal Gel Formulation
M. Ascaso et al. Journal of AOAC International. 2015, 98(1), 27-34.
https://doi.org/10.5740/jaoacint.13-411
