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Afegeix-ho a l'agenda (iCal)
Biophysics of secretory pathway
Fèlix Campelo (felix.campelo@icfo.eu)
Independent Senior Research Fellow at ICFO Institute of Photonic Sciences, The Barcelona Institute of Science and Technology. Spain.
Cells secrete proteins – such as neurotransmitters, cytokines, or collagens – to regulate many aspects of human physiology, from endocrine signaling, to synaptic transmission or the building of tissues. In this talk, I will present two examples of how biophysics can help us get a better understanding of this fundamental cellular process. First, I will describe a mechanism by which tension and mechanical forces can modulate the shaping of intracellular membranes to mediate the export of large secretory proteins. And second, I will briefly discuss how advanced fluorescence microscopy tools can reveal details of protein secretion.