CREB-binding protein (cbp) genes regulate stem cell maintenance and differentiation
![cbp genes function](/planariabcn/sites/default/files/styles/large/public/2021-03/CBP_DevBiol_0.jpg?itok=FswULnds)
Our recent paper describes how planarian CREB-binding protein (cbp) gene family has been expanded in planarians and diversified their functions. Thus, cbp-2 seems to be required for planarian survival and stem cell maintenance whereas cbp-3 appears to regulate the differentiation of many cell lineages. You can read the whole story at:
https://www.sciencedirect.com/science/article/abs/pii/S0012160621000476