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Molecular Biology of Reproduction and Development

 

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Děd Lukáš

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Dr Lukas Ded performed a research Internship in our laboratory between October 1, 2018 and March 31, 2019. His home research center is the Institute of Biotechnology CAS, v.v.i., from
Vestec, Czech Republic. Some representative recent publications from him are as follows:

Frolikova M, Sebkova N, Ded L, Dvorakova-Hortova K. Characterization of CD46 and β1 integrin dynamics during sperm acrosome reaction.
Sci Rep. 2016 Sep 26;6:33714.

Ded L, Sebkova N, Cerna M, Elzeinova F, Dostalova P, Peknicova J, Dvorakova-Hortova K.In vivo exposure to 17β-estradiol triggers premature sperm capacitation in cauda epididymis. Reproduction. 2015 Sep;150(3):X1.

Capkova J, Kubatova A, Ded L, Tepla O, Peknicova J.Evaluation of the expression of sperm proteins in normozoospermic and asthenozoospermic men using monoclonal antibodies. Asian J Androl. 2016 Jan-Feb;18(1):108-13.

Brieño-Enríquez MA, García-López J, Cárdenas DB, Guibert S, Cleroux E, Děd L, Hourcade Jde D, Pěknicová J, Weber M, Del Mazo J.Exposure to endocrine disruptor induces transgenerational epigenetic deregulation of microRNAs in primordial germ cells. PLoS One. 2015 Apr 21;10(4):e0124296.

Zatecka E, Castillo J, Elzeinova F, Kubatova A, Ded L, Peknicova J, Oliva R.The effect of tetrabromobisphenol A on protamine content and DNA integrity in mouse spermatozoa. Andrology. 2014 Nov;2(6):910-7.

Zatecka E, Ded L, Elzeinova F, Kubatova A, Dorosh A, Margaryan H, Dostalova P, Korenkova V, Hoskova K, Peknicova J.
Effect of zearalenone on reproductive parameters and expression of selected testicular genes in mice. Reprod Toxicol. 2014 Jun;45:20-30.

Dorosh A, Tepla O, Zatecka E, Ded L, Koci K, Peknicova J.
Expression analysis of MND1/GAJ, SPATA22, GAPDHS and ACR genes in testicular biopsies from non-obstructive azoospermia (NOA) patients. Reprod Biol Endocrinol. 2013 May 15;11:42.

Elzeinová F, Pěknicová J, Děd L, Kubátová A, Margaryan H, Dorosh A, Makovický P, Rajmon R. Adverse effect of tetracycline and doxycycline on testicular tissue and sperm parameters in CD1 outbred mice. Exp Toxicol Pathol. 2013 Sep;65(6):911-7.

Ded L, Sebkova N, Cerna M, Elzeinova F, Dostalova P, Peknicova J, Dvorakova-Hortova K. In vivo exposure to 17β-estradiol triggers premature sperm capacitation in cauda epididymis. Reproduction. 2013 Mar 7;145(3):255-63.

Zatecka E, Ded L, Elzeinova F, Kubatova A, Dorosh A, Margaryan H, Dostalova P, Peknicova J.Effect of tetrabrombisphenol A on induction of apoptosis in the testes and changes in expression of selected testicular genes in CD1 mice. Reprod Toxicol. 2013 Jan;35:32-9.

Sebkova N, Cerna M, Ded L, Peknicova J, Dvorakova-Hortova K.The slower the better: how sperm capacitation and acrosome reaction is modified in the presence of estrogens. Reproduction. 2012 Mar;143(3):297-307.

Ded L, Dostalova P, Dorosh A, Dvorakova-Hortova K, Peknicova J.Effect of estrogens on boar sperm capacitation in vitro. Reprod Biol Endocrinol. 2010 Jul 13;8:87.