Elnaz Aledavood, Carolina Estarellas and F. Javier Luque have recently published the article entitled "Structural basis of the selective activation of enzyme isoforms: Allosteric response to activators of beta1- and beta2- containing AMPK complexes" in the "Computational and Structural Biotechnology Journal"
The studies in this project aimed to explore the molecular basis of the selective isoform activation of AMPK, especially focusing on the role played by the two different isoforms of beta subunit. They examined the structural and dynamical properties of beta1 and beta2 containing AMPK complexes formed with A-769662 and SC4.
If you want more details about the article, check the link: https://www.sciencedirect.com/science/article/pii/S2001037021002452