RESEARCH AREAS

Recovery of bioactive compounds

Within the framework of the circular bioeconomy, the final objective of this line of research is the design of processes for the recovery of bioactive compounds from agri-food waste, which allows their recovery while reducing their environmental impact.

Research focus:

  • Characterization of the residues
    The identification and quantification of bioactive compounds in different types of agrifood waste, to label the target compounds, is a key issue. Liquid chromatography with UV-vis, fluorescence and mass spectrometry detection is used.
    Likewise, antioxidant and radical scavenger capacities are also evaluated.
  • Extraction and purification of bioactive compounds, mainly polyphenols.
    Greening the extraction step is an objective, and solvents such as water, ethanol, or natural deep eutectic solvents are considered. On the other hand, a range of extraction techniques are assessed.
    The purification of the extracts is highly challenging. Strategies based on membrane separations and on adsorption/elution processes using resins are investigated.

More information on this line of research in the Instagram account @recycle4antiox

PUBLICATIONS

Papers

PAPERS

2024
2023
2022
2021
2020
BEFORE

2024

  • Microwave-assisted extraction with natural deep eutectic solvents for polyphenol recovery from agrifood waste: Mature for scaling-up?
    P. Tapia-Quirós, M. Granados, S. Sentellas, J. Saurina
    Sci. Total Environ. 912 (2024) 168716
    https://doi.org/10.1016/j.scitotenv.2023.168716

 

  • Analysing polypeptide antibiotics residues in animal muscle tissues: The crucial role of HRMS
    A. Rúbies, I. Beguiristain, J. Tibon, N. Cortés-Francisco, M. Granados
    Food Chem. 443 (2024) 138481
    https://doi.org/10.1016/j.foodchem.2024.138481

2023

  • Recovery of phenolic compounds from wine lees using green processing: Identifying target molecules and assessing membrane ultrafiltration performance.
    A. Mir-Cerdà, I. Carretero, J.R. Coves, A. Pedrouso, C.M. Castro-Barros, T. Alvarino, J.L. Cortina, J. Saurina, M. Granados, S. Sentellas
    Science of the Total Environment 857(2023) 159623
    https://doi.org/10.1016/j.scitotenv.2022.159623

 

  • An overview of the extraction and characterization of bioactive phenolic compounds from agri-food waste within the framework of circular bioeconomy
    A. Mir-Cerdà, O.r Nuñez, M. Granados, S. Sentellas, J. Saurina
    Trends in Analytical Chemistry 161 (2023) 116994
    https://doi.org/10.1016/j.trac.2023.116994

 

  • Green Extraction of Antioxidant Compounds from Olive Tree Leaves Based on Natural Deep Eutectic Solvents
    A. Mir-Cerdà, M. Granados, J. Saurina, S. Sentellas
    Antioxidants 12 (2023) 995
    https://doi.org/10.3390/antiox12050995

2022

  • Total Polyphenol Content in Food Samples and Nutraceuticals: Antioxidant Indices versus High Performance Liquid Chromatography.
    O. Vidal-Casanella, J. Moreno-Merchan, M. Granados, O. Nuñez, J. Saurina, S. Sentellas
    Antioxidants 11 (2022) 324
    https://doi.org/10.3390/antiox11020324

 

  • Recovery of Polyphenols from Agri-Food By-Products: The Olive Oil and Winery Industries Cases.
    P. Tapia-Quirós, M.F. Montenegro-Landívar,M. Reig, X. Vecino, J.L. Cortina, J. Saurina, M. Granados
    Foods 11 (2022) 362
    https://doi.org/10.3390/foods11030362

 

  • Integration of membrane processes for the recovery and separation of polyphenols from winery and olive mill wastes using green solvent-based processing
    P. Tapia-Quirós, M.F. Montenegro-Landívar, M. Reig, X. Vecino, J. Saurina, M. Granados, J.L. Cortina
    Journal of Environmental Management, 307 (2022) 114555
    https://doi.org/10.1016/j.jenvman.2022.114555

 

  • A green approach to phenolic compounds recovery from olive mill and winery wastes P. Tapia-Quirós, M.F. Montenegro-Landívar, X. Vecino, T. Alvarino, J.L. Cortina, J. Saurina, M. Granados, M. Reig
    Science of the Total Environment, 835 (2022)155552
    https://doi.org/10.1016/j.scitotenv.2022.155552

 

  • Recovery of Natural Polyphenols from Spinach and Orange By-Products by Pressure-Driven Membrane Processes
    M.F. Montenegro-Landívar, P. Tapia-Quirós, X. Vecino, M. Reig, M.Granados, A. Farran, J.L. Cortina, J. Saurina, C. Valderrama
    Membranes 12 (2022)669
    https://doi.org/10.3390/membranes12070669

 

  • Integration of Nanofiltration and Reverse Osmosis Technologies in Polyphenols Recovery Schemes from Winery and Olive Mill Wastes by Aqueous-Based Processing
    P. Tapia-Quirós, M.F. Montenegro-Landívar, M. Reig, X. Vecino, J. Saurina, M. Granados, J.L. Cortina
    Membranes 12 (2022) 339
    https://doi.org/10.3390/membranes12030339

2021

  • Recovery of Added-Value Compounds from Orange and Spinach Processing Residues: Green Extraction of Phenolic Compounds and Evaluation of Antioxidant Activity.
    M.F. Montenegro-Landívar, P. Tapia-Quirós, X. Vecino, M. Reig, C. Valderrama, M. Granados, J.L. Cortina,J. Saurina
    Antioxidants 10 (2021) 1800
    https://doi.org/10.3390/antiox10111800

 

  • Polyphenols and their potential role to fight viral diseases: An overview.
    M.F. Montenegro-Landívar, P. Tapia-Quirós, X. Vecino, M. Reig, C. Valderrama, M. Granados,J.L. Cortina, J. Saurina
    Science of the Total Environment, 801 (2021) 149719
    https://doi.org/10.1016/j.scitotenv.2021.149719

 

  • Analytical Methods for Exploring Nutraceuticals Based on Phenolic Acids and Polyphenols.
    O. Vidal-Casanella, O. Núñez, M. Granados, J. Saurina, S. Sentellas
    Applied Science 11 (2021) 8276
    https://doi.org/10.3390/app11188276

 

  • Fruit and vegetable processing wastes as natural sources of antioxidant-rich extracts: Evaluation of advanced extraction technologies by surface response methodology,
    M.F. Montenegro-Landívar, P. Tapia-Quirós, X. Vecino, M. Reig, C. Valderrama, M.Granados, J.L. Cortina, J. Saurina
    Journal of Environmental Chemical Engineering, 9 (2021) 105330
    https://doi.org/10.1016/j.jece.2021.105330

2020

  • Olive Mill and Winery Wastes as Viable Sources of Bioactive Compounds: A Study on Polyphenols Recovery.
    P. Tapia-Quirós, M.F. Montenegro-Landívar, M. Reig, X. Vecino, T. Alvarino, J.L. Cortina, J. Saurina, M. Granados
    Antioxidants 9 (2020) 1074
    https://doi.org/10.3390/antiox9111074

BEFORE

2019

  • Exploring the Antioxidant Features of Polyphenols by Spectroscopic and Electrochemical Methods.
    B. Alcalde, M. Granados, J. Saurina
    Antioxidants 8 (2019) 523
    https://doi.org/10.3390/antiox8110523
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